The GOAT ANTI HUMAN AMPK ALPHA 2 Antibody from MyBioSource.com is a Goat Polyclonal antibody to AMPK alpha 2, AMPKa2, PRKAA, and PRKAA2. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, and Porcine antigen. The GOAT ANTI HUMAN AMPK ALPHA 2 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
MBS224265 specifically recognises AMPK alpha 2, otherwise known as PRKAA2, a Serine/threonine-protein kinase and the catalytic subunit of the AMP-activated protein kinase (AMPK), a central metabolic sensor, essential for the regulation of fatty acid and cholesterol synthesis, in response to fluctuations in nutrient and intracellular energy levels. AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, is essential for ULK1-mediated autophagy, and that the phosphorylation of raptor by AMPK, plays an important role in autophagy induction